Thursday, June 13, 2019

'Locking' an arthritis drug may be key to improving it

Attaching a removable lock to an arthritis drug can make it safer and more effective, according to a new study publishing June 13 in the open-access journal PLOS Biology led by Wen-Wei Lin of Kaohsiung Medical University, Taiwan. The findings suggest a new way to improve the efficacy of a drug taken by millions of patients throughout the world.

* This article was originally published here

PoseRBPF: A new particle filter for 6D object pose tracking

Researchers at NVIDIA, University of Washington, Stanford University, and University of Illinois Urbana-Champaign have recently developed a Rao-Blackwellized particle filter for 6-D pose tracking, called PoseRBPF. The approach can effectively estimate the 3-D translation of an object and its full distribution over the 3-D rotation. The paper describing this filter, pre-published on arXiv, will be presented at the upcoming Robotics Science and Systems Conference in Freiburg, Germany.

* This article was originally published here

Behind the magic: Making moving photos a reality

People moving in and out of photographs used to be reserved for the world of Harry Potter. But now computer scientists at the University of Washington have brought that magic to real life.

* This article was originally published here

Fermi mission reveals its highest-energy gamma-ray bursts

For 10 years, NASA's Fermi Gamma-ray Space Telescope has scanned the sky for gamma-ray bursts (GRBs), the universe's most luminous explosions. A new catalog of the highest-energy blasts provides scientists with fresh insights into how they work.

* This article was originally published here

Urbach Tower offers view of self-shaping architecture

Oh, those leaning towers are so yesterday. Tech-watching sites, rather, are talking about a tower that does not lean; it is just as interesting as it is a self twisting tower. This is the Urbach Tower.

* This article was originally published here

Monitoring educational equity

A centralized, consistently reported system of indicators of educational equity is needed to bring attention to disparities in the U.S. education system, says a new report by the National Academies of Sciences, Engineering, and Medicine. Indicators—measures used to track performance and monitor change over time—can help convey why disparities arise, identify groups most affected by them, and inform policy and practice measures to improve equity in pre-K through 12th grade education.

* This article was originally published here

Research shows temperature, glyphosate increase probability for dicamba volatility

Higher temperatures and mixing glyphosate with dicamba lead to increased atmospheric concentrations of dicamba, according to scientists with the University of Tennessee Institute of Agriculture.

* This article was originally published here

The whisper of schizophrenia: Machine learning finds 'sound' words predict psychosis

A machine-learning method discovered a hidden clue in people's language predictive of the later emergence of psychosis—the frequent use of words associated with sound. A paper published by the journal npj Schizophrenia published the findings by scientists at Emory University and Harvard University.

* This article was originally published here

Once thought to be asexual, single-celled parasites caught in the act

Even single-celled organisms desire partners every now and then.

* This article was originally published here

Research reveals liquid gold on the nanoscale

The research published in Nature Communications set out to answer a simple question—how do nanoparticles melt? Although this question has been a focus of researchers for the past century, it still is an open problem—initial theoretical models describing melting date from around 100 years, and even the most relevant models being some 50 years old.

* This article was originally published here

Southwest pushes back expected return of troubled Boeing jet

Southwest Airlines is delaying expectations for return of the Boeing 737 Max, which remains grounded after two deadly crashes.

* This article was originally published here

Uber tests drone food delivery, launches new autonomous SUV

Uber is testing restaurant food deliveries by drone.

* This article was originally published here

Research shows temperature, glyphosate increase probability for dicamba volatility

Higher temperatures and mixing glyphosate with dicamba lead to increased atmospheric concentrations of dicamba, according to scientists with the University of Tennessee Institute of Agriculture.

* This article was originally published here

Mutant bacterial receptor could point to new therapies against opportunistic pathogen

Researchers have developed a new mutant version of a receptor used by a bacterial pathogen for a chemical communication process called quorum sensing, according to a study published June 13 in the open-access journal PLOS Pathogens by Bonnie Bassler of Princeton University, and colleagues. As the authors note, the mutant receptor could be used to identify therapeutic compounds that inhibit quorum sensing, fulfilling an urgent medical need.

* This article was originally published here

Research identifies key driver for infanticide among chimpanzees

Research conducted by the University of Kent has suggested that the sexual selection hypothesis for infanticide may be the key driver for the high rate of infant killings among a community of chimpanzees in Uganda.

* This article was originally published here

A new approach for unsupervised paraphrasing without translation

In recent years, researchers have been trying to develop methods for automatic paraphrasing, which essentially entails the automated abstraction of semantic content from text. So far, approaches that rely on machine translation (MT) techniques have proved particularly popular due to the lack of available labeled datasets of paraphrased pairs.

* This article was originally published here

One-fifth of US surgeons still overusing riskier procedure to create kidney dialysis access

Long-term hemodialysis is a lifesaver for approximately half a million patients in the United States with kidney failure (also known as end-stage renal disease, or ESRD) who are either waiting on or unsuitable for a kidney transplant. But before the external machinery can take over the function of the kidneys—filtering and cleansing wastes from the blood—a minor surgical procedure is needed to create a stable, functional and reusable access to the circulatory system, usually through blood vessels in the arm.

* This article was originally published here

Deadly tick-borne virus cured with experimental flu drug, in mice

Only a few cases of the newly discovered Bourbon virus have been reported, and two of them ended in death, partly because no specific treatments are available for the tick-borne illness. Now, researchers at Washington University School of Medicine in St. Louis have identified an experimental antiviral drug that cures mice infected with the potentially lethal virus. The drug, favipiravir, is approved in Japan but not the U.S. for treatment of influenza, a related virus.

* This article was originally published here

Common conditions keep many patients out of knee cartilage research studies

Some of the most common traits among patients with cartilage issues in the knee are excluding them from participating in clinical trials because the trial outcomes might not yield the optimum results for new methods of cartilage regeneration, according to a Penn Medicine study published in Regenerative Medicine. Researchers testing the new methods tend to only include the patients most likely to succeed with the fewest complications, but if some of these trials could be safely opened up to different kinds of patients—such as those older than 55 or younger than 18, or those who knee joints don't align perfectly—the results could be much more robust and reflective of the patient population being treated. In the team's paper, they also highlighted therapies that hold special promise for the excluded populations, such as the use of "scaffolding" to promote cartilage growth.

* This article was originally published here

Holistic view of planning energy self-sufficient communities

Sustainable communities supplied by local renewable energy production are beginning to be established in the U.S. By using energy-efficient buildings and distributing means of energy generation, such as solar panels, throughout buildings in these districts, the communities manage to produce enough energy for their local needs—achieving a yearly net zero energy (NZE) balance.

* This article was originally published here

German state to shut Facebook page over data privacy worries

A German state government announced plans Thursday to shut down the region's Facebook page because of concerns over the company's handling of data protection issues.

* This article was originally published here

Scientists create 'virtual biopsy' device to detect skin tumors

Using sound vibrations and pulses of near-infrared light, a Rutgers University scientist has developed a new "virtual biopsy" device that can quickly determine a skin lesion's depth and potential malignancy without using a scalpel.

* This article was originally published here

Video games battle for the cloud as industry girds for change

The knock-down, drag-out battle in the video game world heads to the cloud as the premier industry event looks to adapt to a consumer shift to streaming services.

* This article was originally published here

Search and rescue: Researchers on mission to save the coral reefs of South Florida

A research ship that located the black box of a crashed Air France jet has embarked on a scientific expedition to the Florida Keys, where a mysterious disease is burning through coral reefs.

* This article was originally published here

VW says cooperation talks with Ford 'close to completion'

Car giant Volkswagen's talks on co-operation with US-based Ford concerning electric vehicles and automated driving are "close to completion", the German company's chief executive Herbert Diess said Thursday.

* This article was originally published here

VW says cooperation talks with Ford 'close to completion'

Car giant Volkswagen's talks on co-operation with US-based Ford concerning electric vehicles and automated driving are "close to completion", the German company's chief executive Herbert Diess said Thursday.

* This article was originally published here

Q&A: How is fibromyalgia diagnosed?

Dear Mayo Clinic: Is there a specific test to definitively diagnose fibromyalgia? If not, how do doctors confidently diagnose this disorder?

* This article was originally published here

Innovative robot fingers hold promise for assistive living, prosthetics

There's nothing quite like the comforting squeeze of your partner's hand. But a robot's hand? That's perhaps a bit different.

* This article was originally published here

Holistic view of planning energy self-sufficient communities

Sustainable communities supplied by local renewable energy production are beginning to be established in the U.S. By using energy-efficient buildings and distributing means of energy generation, such as solar panels, throughout buildings in these districts, the communities manage to produce enough energy for their local needs—achieving a yearly net zero energy (NZE) balance.

* This article was originally published here

Researchers identify the source of asymmetry in RNA-DNA hybrids

A study headed by the Institute for Research in Biomedicine (IRB Barcelona) and published in the journal CHEM furthers the understanding of the asymmetry between nucleic acid hybrids. This advance may make a significant contribution to improving gene therapies.

* This article was originally published here

Hubble observes tiny galaxy with big heart

Nestled within this field of bright foreground stars lies ESO 495-21, a tiny galaxy with a big heart. ESO 495-21 may be just 3000 light-years across, but that is not stopping the galaxy from furiously forming huge numbers of stars. It may also host a supermassive black hole; this is unusual for a galaxy of its size, and may provide intriguing hints as to how galaxies form and evolve.

* This article was originally published here

Suit alleges Amazon's Alexa violates laws by recording children's voices without consent

A lawsuit filed in Seattle Tuesday alleges Amazon is recording children who use its Alexa devices without their consent, in violation of laws governing recordings in at least eight states, including Washington.

* This article was originally published here

Implanted drug 'reservoir' safely reduces injections for people with macular degeneration

In a clinical trial of 220 people with "wet" age-related macular degeneration, Johns Hopkins Medicine researchers, collaborators from many sites across the country, and Genentech in South San Francisco have added to evidence that using a new implant technology that continuously delivers medication into the eyes is safe and effective in helping maintain vision and reduces the need for injections in the eyes.

* This article was originally published here

Undocumented plant extinctions are a big problem in Australia

A recent survey on the world's plants found a shocking number have gone extinct—571 since 1750. And this is likely to be a stark underestimate. Not all plants have been discovered, so it's likely other plants have gone extinct before researchers know they're at risk, or even know they exist.

* This article was originally published here

Empirical energy consumption model quantifies Bitcoin's carbon footprint

Researchers have conducted the first analysis of Bitcoin power consumption based on empirical data from IPO filings and localization of IP addresses. They found that the cryptocurrency's carbon emissions measure up to those of Kansas City—or a small nation. The study, published June 12 in the journal Joule, suggests that cryptocurrencies contribute to global carbon emissions, an issue that must be considered in climate change mitigation efforts.

* This article was originally published here

Evolving neural networks with a linear growth in their behavior complexity

Evolutionary algorithms (EAs) are designed to replicate the behavior and evolution of biological organisms while solving computing problems. In recent years, many researchers have developed EAs and used them to tackle a variety of optimization tasks.

* This article was originally published here

How an ancient fireside gathering could tackle HIV stigma in Uganda

For 25 years, northern Uganda was devastated by civil war. During this time the area's residents, many of whom belong to the Acholi people, were forced from their homes. They ended up living in internally displaced camps, relying on the World Food Programme and battling a severe shortage of clean water. Hunger, malnutrition and a lack of adequate sanitation facilities took a dreadful toll.

* This article was originally published here

Those who live longer have fewer children

A long life and lots of children—that was quite a common aspiration until not so long ago. But the world of animals reveals that high fertility and longevity are often mutually exclusive: Particularly animals with shorter lifespans are often very fertile while animals that live longer frequently produce fewer offspring. It seems that organisms with limited resources can be either long-lived or very fertile—but they can't be both at the same time. Scientists at the Max Planck Institute for Evolutionary Biology in Plön have now discovered how the trade-off between survival and fertility works. They have found that the average age at reproduction is a measure for the loss of fertility as life expectancy increases.

* This article was originally published here

More research monkeys retire when studies finish

Izzle, Timon, Batman, River and Mars spent years confined to inside of a lab, their lives devoted to being tested for the benefit of human health.

* This article was originally published here

Urbach Tower offers view of self-shaping architecture

Oh, those leaning towers are so yesterday. Tech-watching sites, rather, are talking about a tower that does not lean; it is just as interesting as it is a self twisting tower. This is the Urbach Tower.

* This article was originally published here

UN-ish speeches cooked by artificial intelligence are quite credible

Those who worry about artificial intelligence being so good it spins out of control into making humans robo-victims of cooked lies posing as truth had best ignore the recent study which is sure to disturb their sleep. The paper looks at a successful implementation of AI-generated speeches.

* This article was originally published here

Empirical energy consumption model quantifies Bitcoin's carbon footprint

Researchers have conducted the first analysis of Bitcoin power consumption based on empirical data from IPO filings and localization of IP addresses. They found that the cryptocurrency's carbon emissions measure up to those of Kansas City—or a small nation. The study, published June 12 in the journal Joule, suggests that cryptocurrencies contribute to global carbon emissions, an issue that must be considered in climate change mitigation efforts.

* This article was originally published here

Cyclone veers away from Indian coast

A cyclone that had been heading for western India has veered away, forecasters said Thursday, although costal areas were still expected to be hit by winds gusting up to 160 kilometres (110 miles) per hour.

* This article was originally published here

Verinurad with febuxostat significantly reduces albuminuria and hyperuricaemia in patients with type 2 diabetes

The results of a phase IIa clinical trial presented today at the Annual European Congress of Rheumatology (EULAR 2019) demonstrate a rapid reduction in albuminuria and hyperuricaemia in patients with type II diabetes with combined treatment of verinurad and febuxostat.

* This article was originally published here

Parrot world's endangered heavyweight faces new threat

An unprecedented disease outbreak has pushed the critically endangered kakapo, the world's fattest parrot, closer to extinction, New Zealand scientists said Thursday.

* This article was originally published here

Low vitamin K levels linked to mobility limitation and disability in older adults

Low levels of circulating vitamin K are linked to increased risk of mobility limitation and disability in older adults, identifying a new factor to consider for maintaining mobility and independence in older age, according to a study led by researchers at the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University.

* This article was originally published here

Epilepsy drugs linked to increased risk of suicidal behavior, particularly in young people

Treatment with gabapentinoids—a group of drugs used for epilepsy, nerve pain and anxiety disorders—is associated with an increased risk of suicidal behaviour, unintentional overdose, injuries, and road traffic incidents, finds a study from Sweden published by The BMJ today.

* This article was originally published here