Sunday, March 10, 2019

3-D bioprinted, vascularized proximal tubules mimic the human kidney's reabsorption functions

Every day our kidneys tackle the daunting task of continuously cleaning our blood to prevent waste, salt and excess fluid from building up inside our bodies. To achieve this, the kidneys' approximately one million filtration units (glomeruli) first remove both waste products and precious nutrients from the blood stream, then specialized structures known as the proximal tubules reabsorb the "good" molecules returning them to our bloodstream. While the reabsorptive functions of the proximal tubule can be compromised by drugs, chemicals, or genetic and blood-borne diseases, our understanding of how these effects occur is still limited.

* This article was originally published here